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TOPIC: Kratom and the effects it has on ORGANS HEART, LIVER , KIDNEYS . Long/Short Term

Kratom and the effects it has on ORGANS HEART, LIVER , KIDNEYS . Long/Short Term 3 months 1 week ago #27837

  • Asaro
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Anyone have any information on what the alkaloids from kratom do to the organs from short-term verse long term use. Please if you do not no facts no need to respond. Not trying to be rude but really not looking for opinions.

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Kratom and the effects it has on ORGANS HEART, LIVER , KIDNEYS . Long/Short Term 3 months 1 week ago #27839

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High-dose use for a long time leads to liver damage and kidney failure. Dark urine and yellowing of the skin and eyes are indicators of advanced damage to the liver and kidneys. Kratom specifically harms the liver, but when the organ is less able to process toxins, those toxins are then filtered out by the kidneys; the kidneys are not used to this work, and that can lead to kidney failure among people with liver damage.

Just something that I came acrossed don't know if there is any science backing it up.

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Kratom and the effects it has on ORGANS HEART, LIVER , KIDNEYS . Long/Short Term 3 months 1 week ago #27840

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The function of the liver is detoxification of the blood, converting the nutrients into useful forms and also metabolizing the toxic substances. It does so with the help of certain microsomal enzymes. Kratom is metabolized by the cytochrome p450 system of the liver.

If Kratom is taken in regular doses, it won’t harm the hepatocytes, however larger amounts of Kratom increases the workload load of hepatocytes, this is where the cells fell, and liver toxicity occurs. If the dose of Kratom is reduced, these liver cells start functioning properly. Kratom doesn’t cause liver cirrhosis.

Kratom abuse can cause intrahepatic cholestasis. In this liver disease, there is the abnormal release of bile. However, it is a very rare condition that occurs in Kratom users. It only happens if you have other co-morbidities like hepatitis etc.

On biopsy of the liver, it is seen that the there is a pattern of drug-induced cholestatic injury. The user usually complains of pain on the right side of the upper abdomen. The liver is enlarged and tender. Liver function tests show elevated levels of enzymes especially ALT. The person complains of dark urine, yellowing of skin, nausea, and pain.

The onset of injury is usually within 2 to 8 weeks of Kratom abuse. The user shows symptoms of fatigue, pruritus and dark urine followed by jaundice. Serum bilirubin levels may rise above 20mg/dL. It can be accompanied by acute renal failure and bone marrow toxicity. The disease can be prolonged, but it resolves spontaneously when the dose of Kratom is tapered off.

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Kratom and the effects it has on ORGANS HEART, LIVER , KIDNEYS . Long/Short Term 3 months 1 week ago #27841

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Kratom is responsible for increasing the urinary output the way coffee does. Extensive research shows that Kratom doesn’t cause injury to the renal system. It only causes acute renal failure in very rare cases when the serum bilirubin level is highly raised. According to users, they haven’t experienced any sort of kidney problem. Kidney stone formation due to Kratom intake is a myth.

To prevent damage to any of the organs of the human body, it is necessary that Kratom does not overdose one. It should be noted that when Kratom is taken with other potentiators, the chances of getting organ injury increases. If Kratom is taken continuously, like more than once during a day and the dose is larger than 12-15 grams, then it may cause intrahepatic cholestasis. Therefore, one should keep the following things in mind when burning Kratom;

Avoid taking Kratom extracts.
Avoid overdosing on Kratom.
Avoid using potentiators with Kratom.
Drink a lot of water during the first 5 hours after burning Kratom.
Take healthy diet.
Monitor your liver function tests and renal function tests when consuming Kratom.
In case you have other co-morbidities like hepatitis, liver cirrhosis or liver injury, do not consume Kratom. Even if you do, make sure the dose is small.

To treat a Kratom overdose, no further dose of Kratom should be given. Naloxone should be provided in the case of acute Kratom overdosage. A significant amount of fluids should be given to increase the excretion of the Kratom from the system. The IV line should be saved.

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Kratom and the effects it has on ORGANS HEART, LIVER , KIDNEYS . Long/Short Term 3 months 1 week ago #27843

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HAS ANY ONE EVER EXPERIENCED ANY OF THIS

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Kratom and the effects it has on ORGANS HEART, LIVER , KIDNEYS . Long/Short Term 3 months 1 week ago #27855

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It would help if you would reference where you are getting this info so we can see it in context.

Search on Youtube for videos by Dr. Chris McCurdy. His research shows that Kratom has a excellent safety profile, which is why pharmaceutical companies are so interested in studying the active alkaloids for pain relief.

It is my understanding that most of the pathology often associated with Kratom use is seen in users who already have hepatic or other long standing pathology (and/or drug use). BUT being able to see the source document of the information you have posted here would help me to provide a more informed response.
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Last edit: by bomalley.

Kratom and the effects it has on ORGANS HEART, LIVER , KIDNEYS . Long/Short Term 3 months 1 week ago #27858

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bomalley wrote: It would help if you would reference where you are getting this info so we can see it in context.

Search on Youtube for videos by Dr. Chris McCurdy. His research shows that Kratom has a excellent safety profile, which is why pharmaceutical companies are so interested in studying the active alkaloids for pain relief.

It is my understanding that most of the pathology often associated with Kratom use is seen in users who already have hepatic or other long standing pathology (and/or drug use). BUT being able to see the source document of the information you have posted here would help me to provide a more informed response.


Sorry next time will due I will see if I have it in my history and will repost.
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Kratom and the effects it has on ORGANS HEART, LIVER , KIDNEYS . Long/Short Term 3 months 1 week ago #27873

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Yes this is scary to think about. I was doing 25 grams for months and always worry about this. At first I was worried about my liver because I was getting slight pain, now I'm worried about my kidneys because I've become nauseous throughout the day. The only way to fell better is by forcing myself to puke. If it were salmonella I'm sure I wouldn't have to force myself. You can Google both kidney problems and liver problems swear you have something wrong. I forced myself to puke yesterday and a butterfly rash appeared on my face now I'm obsessing about lupus today :D hate my life. I can see how excessive powder shoved down your throat can make your liver work over load, but when I was worried and got a liver ultrasound they said I just have a fatty liver. Once the pharmacy takes over and runs all their tests and adds all their additives every side effect known to man will become of it.

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Kratom and the effects it has on ORGANS HEART, LIVER , KIDNEYS . Long/Short Term 3 months 1 week ago #27874

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There has been instances of liver damage and kidney problems. Even someone posted about them being one with jaundice within the first two weeks. There's just really no way to actually know because everyone is so different.

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Last edit: by Thefrogshateme.

Kratom and the effects it has on ORGANS HEART, LIVER , KIDNEYS . Long/Short Term 3 months 1 week ago #27875

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Thefrogshateme wrote: There has been instances of liver damage and kidney problems. Even someone posted about them being one with jaundice within the first two weeks. There's just really no way to actually know because everyone is so different.


Need to get a blood test done and have your liver enzymes checked if they're high when you know it's the kratom also have you kidneys checked. I made an appointment for Monday to get a blood test because I've been taking about a grams of enhanced Kratom a day actually 12 grams

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