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TOPIC: Is Kratom considered an opioid?

Is Kratom considered an opioid? 2 weeks 6 days ago #42802

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Ok, I have a friend who is in major pain, constantly. I introduced her to kratom, it's been a godsend to her for the past few months while she has been taking it. Plus I make Kratom salve along with other salves that she buys from me and uses every day. It gives her in her words "amazing relief". So everything is as good for her as can be, she's relatively pain free for the first time in over 15 years. She's up and moving around. She can work in her garden. She can do yard work. She is ecstatic.

So what's the problem you ask? Doctors, big pharma, our government.... oh, sorry, I digress.

The problem is, she had an appointment with her pain management doctor. She had been forgetting to tell this guy that she had added kratom to her over the counter meds she takes. She forgot again, but called as soon as she got home to inform him of this. She received a message from his office a couple of hours later telling her that she could not take the kratom orally or in salve form. That it is an opioid and a controlled substance. That if she continued to take it she would be dropped from his patient list.

Now, I've done a lot of reading about kratom, but obviously not enough. Because I have never read anywhere that it is considered an opioid and the only places it is considered a controlled substance was in the states where it is banned.

Is it an opioid?
Does it show up on a drug panel as an opioid?


This inquiring mind would really like to know. So thanks for your help in answering this....
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Is Kratom considered an opioid? 2 weeks 6 days ago #42805

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It’s an opioid AGONIST (like tramadol/Ultram only totally not).

Actually it only CONTAINS opioid agonist ALKALOIDS.

It’s a controlled substance in OTHER COUNTRIES and has been under threat here for years (still is).

As you mentioned, it IS banned in certain states.

Unfortunately, with the recent wave of propaganda came a lot of misinformed information and uninformed use of the leaf.

It’s been discussed at length on many forums regarding the pain clinic issues, rehab issues and western medication issues. Kratom is a threat to the sales of synthetic products and some pain clinics test for kratom. But the standard opiate test does NOT detect kratom.

There is a lot of discrimination due to monetary agendas that do not benefit from kratom use.

I recommend people read a lot about the plant prior to use. Many ER calls are due to misuse and misunderstanding of what the leaf is and then lawmakers get upset and use these misinformed patient complaints to say kratom is UNSAFE.

Unfortunately the bridge is burned for your friend.

I recommend she discontinue use in order to continue receiving proper medical care.

Next time, please have your friends get INFORMED FIRST. Sorry I’m a bit crabby on the topic because there is a LOT of misuse followed by blaming the substance instead of the user as this botanical is enjoying huge popularity in mainstream places due to propaganda from the FDA backfire.

Here’s a snippet of information from a professional resource that explains it a bit better than I do:

“Both mitragynine and 7-hydroxymitragynine are opioid receptor agonists, similar in effect but chemically different from conventional opioids such as morphine and oxycodone. In this way, kratom has a similar but much weaker analgesic property than conventional opioids. The effect of opioid-agonists is in part related to the specific receptor sub-type they interact with, including delta (δ), kappa (κ), and mu (μ) opioid receptors. Of these three, conventional opioid drugs such as oxycodone primarily target the μ-opioid receptor, which apart from producing an analgesic effect, also promotes respiratory depression, which is a major cause of death from overdose.

Mitragynine exerts the highest affinity for κ-opioid receptors, followed by μ- and δ-opioid receptors, whereas 7-hydroxymitragynine targets primarily the μ-opioid receptor (Suhaimi et al). Compared to morphine mitragynine is only about 26% as potent, whereas 7-hydroxymitragynine is about 10 times more potent than morphine (Takayama et al). With regard to the whole plant, however, kratom has been shown to have 350 times less affinity for the opioid receptor than morphine (Hassan et al 2013), underscoring a clear difference between the isolated alkaloids and the crude herb.

Another important difference between the most potent opioids in kratom, i.e. 7-hydroxymitragynine and its derivatives, is that it by-passes the activity of β-arrestin-2, an intracellular protein that interacts with receptors and signaling pathways to mediate the behavioral effects of opioid drugs.By failing to recruit β-arrestin-2, 7-hydroxymitragynine appears to slow the development of tolerance and physical dependence, demonstrating a dramatic reduction in unwanted side-effects such as respiratory depression and constipation (Váradi et al 2016).

While the presence of mitragynine and 7-hydroxymitragynine in kratom explains its opiate like effects in higher doses, it has been observed that in smaller doses, kratom has stimulatory effects. While this effect isn’t completely understood, it has been shown that the chemical structure of mitragynine incorporates the nucleus of tryptamine, and interacts with serotonergic and adrenergic systems to provide a stimulating, mood-enhancing effect (Adkins et al 2011).”
Laurie
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Is Kratom considered an opioid? 2 weeks 6 days ago #42806

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Also health care insurance companies are unable to profit from kratom sales and they will take unknown action if they know about kratom use.

Check out the discussion from earlier today/yesterday on AKACHAT for more comments and thoughts from other users: akachat.discussion.community/post/tellin...95076?pid=1309397988
Laurie
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Is Kratom considered an opioid? 2 weeks 6 days ago #42807

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Unfortunately you cannot continue pain management at just about every pain clinic and take Kratom. Like doctors forcing you to taper pain meds they force you to decide between herbal treatments and chemicals.Pain clinics lose money just like rehab centers to kratom and the result is spewing out the misinformation the FD A has been providing them scaring you into making a choice.

Kratom has a higher safety profile and for me at least more successful in treating pain. I would never consider a pain clinic. But that was and has always been my decision. I have spinal arthritis and stenosis from failed back surgery. I used cortisone injections for decades for pain management which I do not recommend for anyone.(side effects)

The consideration is does the pain clinic actually offer medical treatment or are they only dispensing meds(and usually now not enough to really control pain and have a quality of life) If the pain clinic is not treating anything except for med dispensing and they haven't improved quality of life your friend she is better off without them.

Knowledge is key go over the link read the discussion, I hope your friend is well and stays comfortable.
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Is Kratom considered an opioid? 2 weeks 6 days ago #42809

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Also please read Paul's blog. Many articles often explains why your doctors are not informed and they are heavily influenced by big pharma.
Humanity vs. the Medical Profit Machine
www.diabetes-symptoms-magic.com/diabetes...1Z9EXs8TZqOzr-hb0GSQ

Pharma controls the education, they are trained to write prescriptions.

Check out this topic. It touches on why I decided to self treat my incredibly painful tendinitis instead of heading out to my orthopedic doctor. I am not anti doctor I actually have a decent relationship with this doctor. I was looking for a curative approach, Kratom only helped the pain I am taking supplements and made progress, its unfortunate that I felt traditional medicine would have led me to a path of injections and possibly surgery.
www.ilovekratom.com/forum/health-and-wel...start=0#.XWNKyuhKiUk

Yes sorta strayed off topic....
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Last edit: by Nan70.

Is Kratom considered an opioid? 2 weeks 6 days ago #42812

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Thanks Nan70! I meant to recommend Paul’s BLOGS also! Thanks for doing so!

You’re awesome!
Laurie
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Last edit: by Laurie.

Is Kratom considered an opioid? 2 weeks 5 days ago #42831

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Thank you everybody for helping me understand better this issue at hand. I'm not the sharpest tool in the shed and sometimes I need to read and re read stuff before it really sinks in. The links and the inserted quotes helped me immensely, so again, Thank YOU!!!!
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Is Kratom considered an opioid? 2 weeks 5 days ago #42832

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Thanks for putting the question out there so other people might check it out! I’m not the sharpest knife in the drawer either. That’s why I still hang around this forum.

I’ll be interested to hear your follow-up and what your friend does to smooth things over with her pain management drs.

I hope I’m still alive when drs are in business because they want to help people enough to encourage less profitable means. There are a few now, but those are rare birds. I hope to see it become mainstream in my lifetime.
Laurie
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Is Kratom considered an opioid? 2 weeks 5 days ago #42837

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LadyGoodWrench:

True scientists say kratom is not an opioid -- or, more specifically, Andrew Kruegel of Columbia University calls it an "atypical opioid" -- meaning it doesn't act like most opium-derived drugs, which is why it doesn't cause the deadly side-effects.

The term opioid has gotten stretched to mean anything that affects opioid receptors in our body (which include chocolate, coffee, mother's milk, and endorphins).

Many pain management clinics have rules of their own against their patients using kratom, so it's probably futile to argue. It doesn't show up on most drug tests, so -- if you hadn't mentioned the salve and kratom -- he probably would not have known.

The American Kratom Association's consultant, Dr. Jack Henningfield, who has done much work for the FDA, National Institutes of Health, etc., says kratom is definitely NOT an opioid, but the former FDA Commissioner Gottlieb, for political reasons chose to say it IS an opioid, so that's probably what your PAin doc is going by.

No, unless they're testing for mitragynine (which is very expensive), it won't show up on a typical urine test.

Pain specialists are a very jealous bunch. It's his way or the highway. Can you guess which one I would choose?

Good luck!
;)
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Is Kratom considered an opioid? 2 weeks 5 days ago #42841

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Just to be safe. I really dont tell anyone I'm using Kratom. It just a misunderstood plant that is not socially acceptable in USA yet. Just like pot was...now its gained acceptance.
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